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Articles (186)
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The relation between 21st-century skills and digital skills: A systematic literature review

van Laar, Ester, van Deursen, Alexander J.A.M., van Dijk, Jan A.G.M., de Haan, Jos

Journal:

Computers in Human Behavior

Année:

2017

Langue:

english

Fichier:

PDF, 481 KB

english, 2017

Senolytic therapies for healthy longevity

van Deursen, Jan M.

Journal:

Science

Année:

2019

Langue:

english

Fichier:

PDF, 301 KB

english, 2019

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Baker, Darren J., Wijshake, Tobias, Tchkonia, Tamar, LeBrasseur, Nathan K., Childs, Bennett G., van de Sluis, Bart, Kirkland, James L., van Deursen, Jan M.

Journal:

Nature

Année:

2011

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2011

21st-Century digital skills instrument aimed at working professionals: Conceptual development and empirical validation

van Laar, Ester, van Deursen, Alexander J.A.M., van Dijk, Jan A.G.M., de Haan, Jos

Journal:

Telematics and Informatics

Année:

2018

Langue:

english

Fichier:

PDF, 896 KB

english, 2018

The first-level digital divide shifts from inequalities in physical access to inequalities in material access

van Deursen, Alexander JAM, van Dijk, Jan AGM

Journal:

New Media & Society

Année:

2018

Langue:

english

Fichier:

PDF, 156 KB

english, 2018

Aneuploidy in Cancer and Aging

Naylor, Ryan M., van Deursen, Jan M.

Journal:

Annual Review of Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 376 KB

english, 2016

Senescent cells: an emerging target for diseases of ageing

Childs, Bennett G., Gluscevic, Martina, Baker, Darren J., Laberge, Remi-Martin, Marquess, Dan, Dananberg, Jamie, van Deursen, Jan M.

Journal:

Nature Reviews Drug Discovery

Année:

2017

Langue:

english

Fichier:

PDF, 579 KB

english, 2017

Internet use in the home: Digital inequality from a domestication perspective

Scheerder, Anique J, van Deursen, Alexander JAM, van Dijk, Jan AGM

Journal:

New Media & Society

Année:

2019

Langue:

english

Fichier:

PDF, 184 KB

english, 2019

Determinants of 21st-century digital skills: A large-scale survey among working professionals

van Laar, Ester, van Deursen, Alexander J.A.M., van Dijk, Jan A.G.M., de Haan, Jos

Journal:

Computers in Human Behavior

Année:

2019

Langue:

english

Fichier:

PDF, 599 KB

english, 2019

Rethinking Internet skills: The contribution of gender, age, education, Internet experience, and hours online to medium- and content-related Internet skills

Alexander J.A.M. van Deursen, Jan A.G.M. van Dijk, Oscar Peters

Journal:

Poetics

Année:

2011

Langue:

english

Fichier:

PDF, 259 KB

english, 2011

Using the Internet: Skill related problems in users’ online behavior

Alexander J.A.M. van Deursen, Jan A.G.M. van Dijk

Journal:

Interacting with Computers

Année:

2009

Langue:

english

Fichier:

PDF, 210 KB

english, 2009

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

Tsukasa Okuda, Jan van Deursen, Scott W Hiebert, Gerard Grosveld, James R Downing

Journal:

Cell

Année:

1996

Langue:

english

Fichier:

PDF, 439 KB

english, 1996

Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

Richard Moriggl, David J Topham, Stephan Teglund, Veronika Sexl, Catriona McKay, Demin Wang, Angelika Hoffmeyer, Jan van Deursen, Mark Y Sangster, Kevin D Bunting, Gerard C Grosveld, James N Ihle

Journal:

Immunity

Année:

1999

Langue:

english

Fichier:

PDF, 389 KB

english, 1999

Toward a Multifaceted Model of Internet Access for Understanding Digital Divides: An Empirical Investigation

van Deursen, Alexander J. A. M., van Dijk, Jan A. G. M.

Journal:

The Information Society

Année:

2015

Langue:

english

Fichier:

PDF, 434 KB

english, 2015

Cellular senescence in aging and age-related disease: from mechanisms to therapy

Childs, Bennett G, Durik, Matej, Baker, Darren J, van Deursen, Jan M

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2015

Deciphering the tumor suppressive mechanisms of Pten

van Ree, Janine H., van Deursen, Jan M.

Journal:

Cell Cycle

Année:

2016

Langue:

english

Fichier:

PDF, 886 KB

english, 2016

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

Jeon, Ok Hee, Kim, Chaekyu, Laberge, Remi-Martin, Demaria, Marco, Rathod, Sona, Vasserot, Alain P, Chung, Jae Wook, Kim, Do Hun, Poon, Yan, David, Nathaniel, Baker, Darren J, van Deursen, Jan M, Campi

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 3.52 MB

english, 2017

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-promoting Myofibroblasts

Dou, Changwei, Liu, Zhikui, Tu, Kangsheng, Zhang, Hongbin, Chen, Chen, Yaqoob, Usman, Wang, Yuanguo, Wen, Jialing, van Deursen, Jan, Sicard, Delphine, Tschumperlin, Daniel, Zou, Hongzhi, Huang, Wei-Ch

Journal:

Gastroenterology

Année:

2018

Langue:

english

Fichier:

PDF, 26.27 MB

english, 2018

Inhibition of ‘jumping genes’ promotes healthy ageing

Childs, Bennett, van Deursen, Jan

Journal:

Nature

Année:

2019

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2019

Inhibition of ‘jumping genes’ promotes healthy ageing

Childs, Bennett, van Deursen, Jan

Journal:

Nature

Année:

2019

Fichier:

PDF, 1.07 MB

2019

Possibilities and Limitations of Fast Temperature Programming as a Route towards Fast GC

Marieke van Deursen, Jan Beens, Carel A. Cramers, Hans-Gerd Janssen

Journal:

Journal of Separation Science

Année:

1999

Langue:

english

Fichier:

PDF, 86 KB

english, 1999

Fast gas chromatography using vacuum outlet conditions

Marieke Van Deursen, Hans-Gerd Janssen, Jan Beens, Peter Lipman, Roy Reinierkens, Gerard Rutten, Carel Cramers

Journal:

Journal of Microcolumn Separations

Année:

2000

Langue:

english

Fichier:

PDF, 221 KB

english, 2000

Group-Type Identification of Oil Samples Using Comprehensive Two- Dimensional Gas Chromatography Coupled to a Time-of-Flight Mass Spectrometer (GC×GC-TOF)

Marieke van Deursen, Jan Beens, Jetse Reijenga, Peter Lipman, Carel Cramers, Jan Blomberg

Journal:

Journal of Separation Science

Année:

2000

Langue:

english

Fichier:

PDF, 99 KB

english, 2000

Nutritional supplementation with N-3 fatty acids and antioxidants in patients with Crohn's disease in remission: Effects on antioxidant status and fatty acid profile

Dr. Bertine J. Geerling, Anita Badart-Smook, Cees Van Deursen, Adriana C. Van Houwelingen, Maurice G. V. M. Russel, Reinhold W. Stockbrügger, Robert-Jan M. Brummer

Journal:

Inflammatory Bowel Diseases

Année:

2000

Langue:

english

Fichier:

PDF, 747 KB

english, 2000

Design considerations for rapid-heating columns applied in fast capillary gas chromatography

Marieke Van Deursen, Hans-Gerd Janssen, Jan Beens, Gerard Rutten, Carel Cramers

Journal:

Journal of Microcolumn Separations

Année:

2001

Langue:

english

Fichier:

PDF, 155 KB

english, 2001

Influence of Dose on Risk of Acute Urinary Retention After Iodine-125 Prostate Brachytherapy

Ellen M.A. Roeloffzen, Jan J. Battermann, Marijke J.H. van Deursen, Evelyn M. Monninkhof, Mareije I. Visscher, Marinus A. Moerland, Marco van Vulpen

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2011

Langue:

english

Fichier:

PDF, 417 KB

english, 2011

A compressed-domain approach for shot boundary detection on H.264/AVC bit streams

Sarah De Bruyne, Davy Van Deursen, Jan De Cock, Wesley De Neve, Peter Lambert, Rik Van de Walle

Journal:

Signal Processing: Image Communication

Année:

2008

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2008

Use of gene targeting for compromising energy homeostasis in neuro-muscular tissues: The role of sarcomeric mitochondrial creatine kinase

Karen Steeghs, Arend Heerschap, Arnold de Haan, Wim Ruitenbeek, Frank Oerlemans, Jan van Deursen, Benjamin Perryman, Dirk Pette, Marloes Brückwilder, Jolande Koudijs, Paul Jap, Bé Wieringa

Journal:

Journal of Neuroscience Methods

Année:

1997

Langue:

english

Fichier:

PDF, 2.48 MB

english, 1997

CREB1 and CREB-binding protein in striatal medium spiny neurons regulate behavioural responses to psychostimulants

Heather B. Madsen, Srigala Navaratnarajah, Jessica Farrugia, Elvan Djouma, Michelle Ehrlich, Theo Mantamadiotis, Jan Van Deursen, Andrew J. Lawrence

Journal:

Psychopharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 642 KB

english, 2012

The role of muscle spindles in ankle movement perception in human subjects with diabetic neuropathy

R. W. M. van Deursen, Maria Matilde Sanchez, Jan S. Ulbrecht, P. R. Cavanagh

Journal:

Experimental Brain Research

Année:

1998

Langue:

english

Fichier:

PDF, 255 KB

english, 1998

Intercomparison of stranded seeds and loose seed from seedselectron

Jan J. Battermann, Marco Van Vulpen, Marinus A. Moerland, Marijke Van Deursen, Ina Jurgenliemk-Schulz

Journal:

Brachytherapy

Année:

2008

Langue:

english

Fichier:

PDF, 40 KB

english, 2008

Fat tissue, aging, and cellular senescence

Tamara Tchkonia, Dean E. Morbeck, Thomas Von Zglinicki, Jan Van Deursen, Joseph Lustgarten, Heidi Scrable, Sundeep Khosla, Michael D. Jensen, James L. Kirkland

Journal:

Aging Cell

Année:

2010

Langue:

english

Fichier:

PDF, 338 KB

english, 2010

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

Thierfelder, William E., van Deursen, Jan M., Yamamoto, Koh, Tripp, Ralph A., Sarawar, Sally R., Carson, Richard T., Sangster, Mark Y., Vignali, Dario A. A., Doherty, Peter C., Grosveld, Gerard C.

Journal:

Nature

Année:

1996

Fichier:

PDF, 1.03 MB

1996

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis

Kasper, Lawryn H., Boussouar, Fayçal, Ney, Paul A., Jackson, Carl W., Rehg, Jerold, van Deursen, Jan M., Brindle, Paul K.

Journal:

Nature

Année:

2002

Langue:

english

Fichier:

PDF, 638 KB

english, 2002

The Rae1–Nup98 complex prevents aneuploidy by inhibiting securin degradation

Jeganathan, Karthik B., Malureanu, Liviu, van Deursen, Jan M.

Journal:

Nature

Année:

2005

Langue:

english

Fichier:

PDF, 432 KB

english, 2005

Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

Fu, Zheng, Malureanu, Liviu, Huang, Jun, Wang, Wei, Li, Hao, van Deursen, Jan M., Tindall, Donald J., Chen, Junjie

Journal:

Nature Cell Biology

Année:

2008

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2008

Chfr is required for tumor suppression and Aurora A regulation

Yu, Xiaochun, Minter-Dykhouse, Katherine, Malureanu, Liviu, Zhao, Wei-Meng, Zhang, Dongwei, Merkle, Carolin J, Ward, Irene M, Saya, Hideyuki, Fang, Guowei, van Deursen, Jan

Journal:

Nature Genetics

Année:

2005

Langue:

english

Fichier:

PDF, 412 KB

english, 2005

Cytoarchitectural and metabolic adaptations in muscles with mitochondrial and cytosolic creatine kinase deficiencies

Karen Steeghs, Frank Oerlemans, Arnold de Haan, Arend Heerschap, Lia Verdoodt, Martine de Bie, Wim Ruitenbeek, Ad Benders, Carolina Jost, Jan van Deursen, Peter Tullson, Ronald Terjung, Paul Jap, Wim

Journal:

Molecular and Cellular Biochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 787 KB

english, 1998

Characterization of Plasmodium falciparum sexual stage antigens and their biosynthesis in synchronised gametocyte cultures

Arno N. Vermeulen, Jan van Deursen, Ruud H. Brakenhoff, Ton H.W. Lensen, Thivi Ponnudurai, Joseph H.E.Th. Meuwissen

Journal:

Molecular and Biochemical Parasitology

Année:

1986

Langue:

english

Fichier:

PDF, 1.83 MB

english, 1986

Rb Loss Causes Cancer by Driving Mitosis Mad

Jan M. van Deursen

Journal:

Cancer Cell

Année:

2007

Langue:

english

Fichier:

PDF, 279 KB

english, 2007

Whole Chromosome Instability Caused by Bub1 Insufficiency Drives Tumorigenesis through Tumor Suppressor Gene Loss of Heterozygosity

Darren J. Baker, Fang Jin, Karthik B. Jeganathan, Jan M. van Deursen

Journal:

Cancer Cell

Année:

2009

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2009

The mitotic checkpoint in cancer and aging: what have mice taught us?

Darren J Baker, Junjie Chen, Jan MA van Deursen

Journal:

Current Opinion in Cell Biology

Année:

2005

Langue:

english

Fichier:

PDF, 248 KB

english, 2005

Whole chromosome instability and cancer: a complex relationship

Robin M. Ricke, Janine H. van Ree, Jan M. van Deursen

Journal:

Trends in Genetics

Année:

2008

Langue:

english

Fichier:

PDF, 992 KB

english, 2008

The role of cutaneous information in a contact control task of the leg in humans

Robert W.M. van Deursen, Peter R. Cavanagh, Gerrit Jan van Ingen Schenau, Mary B. Becker, Jan S. Ulbrecht

Journal:

Human Movement Science

Année:

1998

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1998

Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency

Ningling Kang-Decker, Caili Tong, Fayçal Boussouar, Darren J Baker, Wu Xu, Alexey A Leontovich, William R Taylor, Paul K Brindle, Jan M.A van Deursen

Journal:

Cancer Cell

Année:

2004

Langue:

english

Fichier:

PDF, 890 KB

english, 2004

Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes

Diederik van Deursen, Gert-Jan Botma, Hans Jansen, Adrie JM Verhoeven

Journal:

BMC Genomics

Année:

2007

Langue:

english

Fichier:

PDF, 526 KB

english, 2007

Selection and characterization of randomly produced mutants of gene V protein of bacteriophage M13

Alphons P. M. STASSEN, Guido J. R. ZAMAN, Jan M. A. van DEURSEN, John G. G. SCHOENMAKERS, Ruud N. H. KONINGS

Journal:

FEBS Journal

Année:

1992

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1992

Integrating dynamic environmental models in GIS: The development of a Dynamic Modelling language

CEES G WESSELUNG, DERC-JAN KARSSENBERG, PETER A BURROUGH, WILLEM P A VAN DEURSEN

Journal:

Transactions in GIS

Année:

1996

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1996

The Nucleoporin CAN/Nup214 Binds to both the Cytoplasmic and the Nucleoplasmic Sides of the Nuclear Pore Complex in Overexpressing Cells

Judith M. Boer, Jan M.A. van Deursen, Huib J. Croes, Jack A.M. Fransen, Gerard C. Grosveld

Journal:

Experimental Cell Research

Année:

1997

Langue:

english

Fichier:

PDF, 420 KB

english, 1997

Effects of the creatine analogue β-guanidinopropionic acid on skeletal muscles of mice deficient in muscle creatine kinase

Jan van Deursen, Paul Jap, Arend Heerschap, Henk ter Laak, Wim Ruitenbeek, Bé Wieringa

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

1994

Langue:

english

Fichier:

PDF, 2.85 MB

english, 1994